1. 這篇文章大概描述(中文30字)....
氧化壓力於腫瘤細胞的角色眾說紛紜，不可否定的是腫瘤細胞具有較高的
自由基/ROS耐受度。然而，近年在許多研究中也將氧化壓力的調控納入腫
瘤治療的方法之一。其中，對於微核醣核酸(microRNA)在細胞凋亡及細胞
命運(cell fate)中所扮演的角色，仍有許多機制與爭議。
This article majorly described that microRNA-183/96/182 cluster
could enhance the chemosensitivity of glioma thru a ROS-mediated
manner. Three target genes were estimated to be regulated by the
shared transcript (the cluster), including FGF9, CPEB1, and FOXO1.
Once the targets got released by the cluster/individual KD, p53-
dependent apoptotic pathway would be triggered; hence, the cancer
went down.
[期刊名稱 與 標題卷號年份等資訊]
The miR-183/96/182 Cluster Regulates Oxidative Apoptosis and
Sensitizes Cells to Chemotherapy in Gliomas
Curr Cancer Drug Targets. 2013 Feb;13(2):221-31
[期刊網址/ 太長的話 請到http://tinyurl.com縮網址]
http://www.ncbi.nlm.nih.gov/pubmed/23252827
[我的e-mail]
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I'm very interested in ROS/microRNA regulation, if any of you have
the similar interests, it is glad to have any kind of discussion
with you guys at all times, appreciate!!
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