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老師一時口誤 W8共筆 第16頁的第七行改成 Finasteride(Proscar) ,是抑制 5-α reductase type Ⅱ. Dutasteride (Avodart) 是抑制 5-α reductase type Ⅰ and type Ⅱ. 這裡還是口誤 BPH 主要是 type Ⅱ 5-α reductase , 而Ca. of prostate, type I 5-α reductase表現較強。 我附原文,先說結論: 跟共筆結論一樣 finasteride沒有加強anti androgeen,LHRH analog的功效 Avodart沒有人做 Combined androgen blockage (CAB) defined as LHRH analogue (ororchiectomy) + antiandrogen。 A few clincal trials with small amount of patients related to Antiandrogen+ finasteride or T riple androgentionblockage [ LHRH analogue (or orchiectomy) + antiandrogen+finasteride ] were conducted in 1995-1999. It can't prove that finasteride have synergastic effect with antiandrogen(or+LHRH analogue). However, no clinical trial test Avodart (type I and type II 5-αreductase inhibitor) s ynergastic effect with antiandrogen (or+LHRHanalogue) f or advanced prostate cancer. 然後老師有參考資料給我們,乖寶寶就看一下吧 http://0rz.tw/sd3Ws http://0rz.tw/zs2tr http://0rz.tw/1IpzE http://0rz.tw/lAUTd http://0rz.tw/H6woK -- ※ 發信站: 批踢踢實業坊(ptt.cc) ◆ From: 122.118.39.175 ※ 編輯: pphank 來自: 122.118.39.175 (03/12 23:50) ※ 編輯: pphank 來自: 122.118.47.241 (03/14 11:54)