原題如下
a) Draw the structures of benzo[a]pyrene and of the two main products of
epoxidation, 4,5-benzo[a]pyrene oxide and 7,8-benzo[a]pyrene oxide.
b) Describe how 7,8-benzo[a]pyrene oxide is converted into the active
"diol epoxide" carcinogen. Discuss the possible reaction of this
"diol epoxide" with the amino group of 2'-deoxyguanosine.
c) What trend has been observed between the number of rings and the
reactivity of polynuclear aromatic hydrocarbons?
a,b 已解決
參考答案
http://herkules.oulu.fi/isbn9514270398/html/x203.html
想請教c該如何回答?
個人的想法是 越多環越容易穩定radical or carbocation
所以越多環 reactivity會越高
謝謝~
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