[情報] "為什麼DNA比RNA穩定?" 的答案

[aaaw (alal)]

主要就是因為DNA沒有2' OH基, 所以不會攻擊磷酯鍵,
造成裂解(auto-catalytic cleavage),RNA則相反,故DNA較穩定.

原文整理:
The chemical difference between RNA and DNA (without 2’ hydroxyl group) makes
 DNA a good permanent information storage molecule, while RNA is used for
 temporary information storage.
Because ribose has both 2’ and 3’ hydroxyl groups, the 2’ hydroxyl group can
 attack the phosphodiester bond in the presence of hydroxyl radicals, which
 results in the phosphate backbone being broken. This reaction can occur
 spontaneously at neutral pH and is called auto-catalytic cleavage.
Because DNA does not have a 2’ hydroxyl group, DNA molecules cannot undergo
 auto-catalytic cleavage, and are therefore much more stable than RNA.

原本找到的網址沒有記下來, 不過大概就是這樣了.
祝大家考試順利!

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