看板 Med93_Conote 關於我們 聯絡資訊
p15第一個菱形的前三行 是根據老師上課所述,語意可能不太清楚 另補充於下; 1.{wikipedia} The primary glutamate receptor is specifically sensitive to N-Methyl-D-Aspartate (NMDA), which causes direct action of the central pore of the receptor, an ion channel, to drive the neuron to depolarize. There are many specific subtypes of glutamate receptors, and it is customary to refer to primary subtypes by a chemical which binds to it more selectively than glutamate. 2.{Tachibana and Kaneko, 1988, Schwartzand Tachibana, 1990} Though glutamate will bind onto all glutamate receptors, each receptor is characterized by its sensitivity to specific glutamate analogues and by the features of the glutamate-elicited current. Glutamate receptor agonists and antagonists are structurally similar to glutamate , which allows them to bind onto glutamate receptors. These compounds are highly specific and, even in intact tissue, can be used in very low concentrations because they are poor substrates for glutamate uptake systems 簡單的說,gluramate receptors中的ionotropic receptors,根據receptors的 selectivity以及那些selective agonists的作用, 可再分為三種subtypes;NMDA、KA、AMPA。 p16的圖片(A1 A2 B1 B2)都是指骨骼肌收縮的例子 請將最後一行的(見下圖B1 B2)移到倒數第五行 -- ※ 發信站: 批踢踢實業坊(ptt.cc) ◆ From: 140.112.206.177