交通大學、清華大學
統計學研究所
專題演講
題 目：Using Comparative Genomics to Predict Disease-Relevant Genes
主講人：Dr. Juan Antonio Gabaldon Estevan
Centre for Genomic Regulation (Barcelona, Spain)
時 間：98年8月18日(星期二)下午15:00-15:50
(下午14:40-15:00茶會於交大統計所429室舉行)
地 點：交大綜合一館427室
Abstract
The era of genomics has opened new possibilities for the computational
prediction of protein function. In particular, the comparison of fully
sequenced genomes allows us to investigate the so-called genomic context of a
gene, which includes its chromosomal positioning relative to other genes as
well as its evolutionary record among the genomes considered. This
information can be exploited to find functionally interacting partners for a
protein of unknown function and thus obtain information on the biological
process in which it is playing a role. I will highlight some examples from
our own research which include the finding of novel genes involved in
mitochondrial dysfunction and the search for novel virulence pathways in
pathogenic fungi.
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※ 編輯: austinly 來自: 140.113.114.244 (08/17 19:55)