Which following statement about "thalassemia" is NOT true?
(A) Obvious clinical manifestation for B-thalassemia major is usually
in the age of 1~2 y/o
(B) A-thalassemia was also called Cooley anemia, the proportion of HbF
was more than 90%
(C) About thalassemia major, congestive heart failure or bone deformities
can be prevented by blood transfusion to keep Hb>10 g/dL
(D) Splenectomy could be considered if the need amount of blood transfusion
is more than 240 ml pRBC/Kg/year
Ans: (B)，應該為B-thalassemia
Which following statement about "thalassemia" is NOT true?
(A) Thalassemia is a kind of single gene disorder, mostly passed by
Autosomal recessive pattern of inheritance
(B) Heterozygous genes for B-thalassemia often referred to thalassemia minor
(C) A-Thalassemia mostly results from gene defect of deletion
(D) If HbA2 more than 4%, B-thalassemia major could be considered.
Ans: (D)，major多顯著增加HbF，minor多顯著增加HbA2
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※ 編輯: Jefong 來自: 61.229.43.149 (05/25 23:26)