Researchers say smokers with heavily wrinkled faces are 5 times more likely
than those without pronounced facial lines to suffer from chronic obstructive
pulmonary disease (COPD), which includes bronchitis and emphysema. The
disease is caused by smoking, which also prematurely ages the skin. Because
COPD develops gradually, researchers say wrinkles could signal its presence
before it is diagnosed.
http://www.thefreedictionary.com/
i think it is not evidence base
只是貼來看看而已
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