推 Shaniece:其實我覺得有些都是以訛傳訛耶,像是大分子會比滴定頭大嗎 04/19 00:45
→ Shaniece:有學過化學就知道分子大小跟公分比是10的n次方,說會破壞 04/19 00:49
→ Shaniece:有點誇張... 04/19 00:54
http://tinyurl.com/clwl6h
白蛋白：
含575個基酸，分子量約65 kd，它負責了血漿滲透壓的 70-80%，常用有5%
精密bag還沒這麼強會破壞分子
Serum albumin
Main article: Serum albumin
The most well-known type of albumin is serum albumin. It is usually found in
the blood or serum (providing its name) but it can also appear in other fluid
compartments (providing the basis for the CSF/serum albumin ratio, for
example.)
Serum albumin is the most abundant blood plasma protein and is produced in
the liver and forms a large proportion of all plasma protein. The human
version is human serum albumin, and it normally constitutes about 60% of
human plasma protein.
Serum albumins are important in regulating blood volume by maintaining the
oncotic pressure (also known as colloid osmotic pressure) of the blood
compartment. They also serve as carriers for molecules of low water
solubility this way isolating their hydrophobic nature, including lipid
soluble hormones, bile salts, unconjugated bilirubin, free fatty acids
(apoprotein), calcium, iron (transferrin), and some drugs like warfarin,
phenobutazone, clofibrate & phenytoin. Competition between drugs for albumin
binding sites may cause drug interaction by increasing the free fraction of
one of the drugs, thereby affecting potency.
Specific types include:
human serum albumin
bovine serum albumin (cattle serum albumin) or BSA, often used in medical and
molecular biology labs.
Low albumin (hypoalbuminaemia) may be caused by liver disease, nephrotic
syndrome, burns, protein-losing enteropathy, malabsorption, malnutrition,
late pregnancy, artefact, genetic variations and malignancy.
High albumin is almost always caused by dehydration. In some cases of retinol
(Vitamin A) deficiency the albumin level can become raised to High-normal
values (ex: 4.9 g/dL). This is because retinol causes cells to swell with
water (this is also the reason too much Vitamin A is toxic).[1] In lab
experiments it has been shown that All-trans retinoic acid down regulates
human albumin production[2]
Normal range of human serum albumin in adults (> 3 y.o.) is 3.5 to 5 g/dL.
For children less than three years of age, the normal range is broader,
2.5-5.5 g/dL.[3]
Albumin binds to the cell surface receptor Albondin.
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