※ 引述《tiniwiel (tiniwiel)》之銘言：
: ※ 引述《peter3752001 (手黑的腳白佑)》之銘言：
: : 讀季瑋珠老師的那份講義
: : 有些問題
: : 請知道的同學或路過的學長姐
: : 幫忙解惑吧
: : 衛導不好念,但是要普救世人
: : 就要咬牙撐過去啊~~~(感冒中,喉嚨痛)
: : 1.P.2中間左邊那張ppt
: : literature retrieval and exclusion criteria是什麼意思?
: : 2.P.4中間右邊那張"基本設計"的對照組
: : 下面寫說跟個案對照方法的對照不同
: : 是哪裡不同?
:
: : 3.同上頁右下 依照時間
: : 同時是怎麼對照?
: : 歷史又是怎麼對照?
: 我在網路上找到的資料...可以參考一下啦
: 雖然是英文的 但我覺得他解釋得滿清楚的
: historical control:
: The results of treatment with the test drug
: are compared with experience historically derived from the adequately
: documented natural history of the disease or condition, or from the
: results of active treatment, in comparable patients or populations.
: Because historical control populations usually cannot be as well
: assessed with respect to pertinent variables as can concurrent control
: populations, historical control designs are usually reserved for special
: circumstances. Examples include studies of diseases with high and
: predictable mortality (for example, certain malignancies) and studies in
: which the effect of the drug is self-evident (general anesthetics, drug
: metabolism).
: : 4.P.5左下
: : 納入跟排除條件在說什麼?
: Inclusion and exclusion criteria are a means of establishing precision
: in your cohort or case-control study. For example, you might suspect that
: a new brand of insulin tablet is more effective than an existing brand,
: but for some reason this seems to be true only for diabetic patients that
: are not overweight by more than 10%. Your professional knowledge has
: produced a "hunch" that has you well on your way to establishing inclusion
: and exclusion criteria.
: Inclusion criteria are the criteria for including a patient in the study,
: and it is important that these criteria be clearly defined in an objective
: manner, so that anyone involved in the study (or anyone attempting to
: replicate the study) can reproduce patient inclusion decisions precisely.
: In other words, can you write down the inclusion criteria so that anyone else
: with professional knowledge similar to your own would include the same patients
: you included?
: The example above, of the new insulin tablet versus an existing one, could be
: translated into an inclusion criteria by specifying the two drugs (e.g. brand
: name, generic and manufacturer name, possibly even lot number).
: Exclusion criteria are the criteria for excluding patients from the study.
: From the example above, the 10% overweight criterion could serve as the basis
: for a specific exclusion criteria statement. As in the case of inclusion
: criteria, is your specification precise enough that someone with knowledge
: similar to your own would exclude the same patients you choose to exclude?
: : 5.P.6右上
: : 事件是最終的終點
: : 二分法則是叫硬性終點
: : 所以事件不等於硬性終點吧(是二分法才是)?
: : 6.同上張
: : 設限資料跟存活分析是什麼?
: : (雖然不會考這麼細,但是可不可以稍微講一下)
存活分析:事件/事件史資料(二分法 硬性終點)加上時間軸 就成為存活分析了吧
: : 7.Basic approaches是在講什麼的方法?
囧
: : 8.P.7右上
: : 何謂干擾因素?
: : 為什麼說結果比流行病學研究可信?
: : (那現在說的是什麼方法在跟流行病學研究比?)
: : 9.同上頁中間左邊那張
: : 為什麼加入時間就變存活分析?
應該就可以畫曲線圖表示 在某一時間點個體的生死吧(此處的硬性終點應該是存活/死亡)
: : 10.同上頁左下
: : Marginal是什麼意思?
: : 11.P.8右上
: : 非標準實驗方法又稱準實驗方法???
: : 12.P.9
: : 實驗方法有很多種而藥物臨床試驗只是其中一種,對嗎?
: : 實驗方法等不等於實驗流行病學?
請向阿湯哥借"公共衛生學" 今天看了裡面有實驗流病學的解釋喔
: : 問題頗多發現自己好像讀太細了~
: : 捉不到重點啊~
: 你真的讀的很細！！讓我發現自己很多地方都沒看清楚...
: 呵呵～大家加油！！
問題 第二頁左上outcomes in outcome management 是啥意思捏
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