新聞講的應該是這一篇喔，Lancet有sars專區，一進去就看到了
http://image.thelancet.com/extras/03art4432web.pdf
以下是摘要
----------------------------------------------------------------------------
Summary
Background
We investigated the temporal progression of the clinical, radiological,
and virological changes in a community outbreak of severe acute respiratory
syndrome (SARS).
Methods
We followed up 75 patients for 3 weeks managed with a standard
treatment protocol of ribavirin and corticosteroids, and assessed the pattern
of clinical disease, viral load, risk factors for poor clinical outcome,
and the usefulness of virological diagnostic methods.
Findings
Fever and pneumonia initially improved but 64 (85%) patients
developed recurrent fever after a mean of 8·9 (SD 3·1) days, 55 (73%) had
watery diarrhoea after 7·5 (2·3) days, 60 (80%) had radiological worsening
after 7·4 (2·2) days, and respiratory symptoms worsened in 34 (45%) after
8·6 (3·0) days. In 34 (45%) patients, improvement of initial pulmonary
lesions was associated with appearance of new radiological lesions at other
sites. Nine (12%) patients developed spontaneous pneumomediastinum and 15
(20%) developed acute respiratory distress syndrome (ARDS) in week 3.
Quantitative reverse-transcriptase (RT) PCR of nasopharyngeal aspirates in
14 patients (four with ARDS) showed peak viral load at day 10, and at day 15
a load lower than at admission. Age and chronic hepatitis B virus infection
treated with lamivudine were independent significant risk factors for
progression to ARDS (p=0·001). SARS-associated coronavirus in faeces was
seen on RT-PCR in 65 (97%) of 67 patients at day 14. The mean time to
seroconversion was 20 days.
Interpretation
The consistent clinical progression, shifting radiological infiltrates,
and an inverted V viral-load profile suggest that worsening in week 2 is
unrelated to uncontrolled viral replication but may be related to
immunopathological damage
--
全文還沒看，請大家自己加油
--
從現在起 流浪是我的名字
--
※ 發信站: 批踢踢實業坊(ptt.csie.ntu.edu.tw)
◆ From: 218.184.116.147