作者canpower222 (布衣)
看板VET_97
標題[學業] 藥理
時間Wed Mar 23 01:02:15 2011
原先是只打算做個簡易版自己看 但有人推薦還是給大家 所以就又PO版了
不過這算是簡易中的簡易 請不要太挑剔 有些地方寫得很鳥就是了
有錯煩請指正 感謝
一、 Opioids
1.Morphine: agonist
2.Codeine: agonist, 治療咳嗽
3.Hydromorphone: agonist
4.Oxymorphone: agonist, used in combination with triflupromazine for
neuroleptanalgesia (FDA approved use in dogs & cats)
5.Meperidine: agonist
6.Fentanyl: agonist, used in combination with droperidol for
neuroleptanalgesia
7.Etorphine: agonist, wild & exotic speices (FDA), used only when
diprenophine or other suitable antagonists are available
8.Buprenorphine: partial agonist for μ receptors
9.Pentazocine (Sosegon): mixed, κ agonist and weak μ antagonist
10.Butorphanol: mixed, κ agonist and weak μ antagonist
11.Nalbuphine: mixed, κ agonist and μ antagonist
12.Nalorphine: mixed, antagonize typical respiratory depression induced by
opioids
13.Naloxone: antagonist
14.Diprenorphine: antagonist, reverse etorphine in wild animals
二、 Preanesthetic Medications
1. Anticholinergic
2. Phenothiazine
3. Butyrophenone
4. Benzodiazepine
5. α2-Adrenergic Agonist
6. Opioid
三、 Local Anesthetics
1.Procanie
2.Benzocaine: 魚
3.Chloroprocaine: 產科
4.Tetracaine
5.Lidocaine: 常用
6.Prilocaine: 過量會methemoglobinemia
7.Bupivacaine: 產科
8.Etidocaine
9.Ropivacaine
四、 Anticonvulsants
1.Phenobarbital: grand mal, partial seizure & status epilepticus, second line
2.Primidone: converted to phenobarbital in vivo
3.Benzodiazepines: absence seizure ,myoclonic seizure & status epilepticus
4.Phenytoin (diphenylhydantoin): Na+ channel blocker, broad spectrum (except
absence seizure) but narrow therapeutic window
5.Carbamazepine: Na+ channel blocker, partial seizure
6.Valproic acid: Na+ channel blocker, tonic-clonic, absence, myoclonic&
partial seizures, second line
7.Ethosuximide: Reduce Ca+2 currents in thalamic neurons, first line drug
for absence seizure
8.Potassium bromide: through chloride channels and hyperpolarizing neurons,
first line
五、 CNS Stimulants
1.Ephedrine: nasal decongestant
2.Amphetamine: release NE and DA & block reuptake, 減肥、治療ADHD
3.Methylphenidate (Ritalin): 治療ADHD
4.Sibutramine (諾美婷; Reductil): 減肥
5.Orlistat (羅氏纖/鮮 Xenical): 減肥
6.Cocaine
7.Methylxanthine: Caffeine (competitive inhibitor for adenosine A1
receptors), Theophylline(支氣管擴張) & Theobromine
8.Nicotine
9.Strychnine: inhibit glycine, induces tonic convulsion
10.Picrotoxin (Picrotoxinin + Picrotin): inhibit GABA, induces clonic and
tonic (high dose) convulsion
11.Doxapram: excite brainstem neurons, respiratory analeptic used in dogs,
cats and horses (FDA), good safety margin between analeptic dose and
convulsant dose, 難產或剖腹產後給新生兒
12.4 Aminopyridine (4 AP): 機制不明
六、 Antidepressants
1.Tyramine: release of stored monoamines
2.Clorgyline: MAO-A inhibitor
3.Selegiline: MAO-B inhibitor, treat pituitary-dependent
hyperadrenocorticism (dopamine deficiency) in dogs, and Parkinson’s disease
in humans
4.Imipramine: tricyclic antidepressant (TCA), block neuronal reuptake of
5-HT & NE (but not DA)
5.Clomipramine: tricyclic antidepressant, separation anxiety in dogs (FDA)
6.Amitriptyline: tricyclic antidepressant
7.Doxepin: tricyclic antidepressant
8.Paroxetine: SSRI
9.Fluoxetine: SSRI, Prozac
10.Sertraline: SSRI
七、 Autocoids & Antagonists
1.Histamine: 測試氣管過敏
2.Pentagastrin: 測試胃酸分泌
3.Betazole: 胃分泌
4.Cromolyn: mast cell stabilizer
5.Nedocromil: mast cell stabilizer
6.Diphenhydramine: first-generation agent
7.Chlorpheniramine: first-generation agent
8.Promethazine: first-generation agent
9.Cyclizine: first-generation agent
10.Terfenadine: second-generation agent
11.Astemizole: second-generation agent
八、 Serotonin & Antagonists
1.Melatonin
2.Buspirone: 5-HT1A agonist, anxiolytic
3.Sumatriptan: 5-HT1B/1D agonist, anti-migraine
4.Cyproheptadine: block 5-HT and H1, 促進食慾
5.Ketanserin: block 5-HT1C/2 and α1, 降高血壓
6.Ondansetron: 5-HT3 blocker, 止吐
7.Tropisetron: 5-HT3 blocker, 止吐
8.Granisetron: 5-HT3 blocker
9.Dolasetron: 5-HT3 blocker
10.Cisapride: 5-HT4 agonist, 腸胃道蠕動
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※ 編輯: canpower222 來自: 140.112.4.189 (03/24 12:26)