※ 引述《cecropin (乾坤一擲)》之銘言：
: 74.遲發性運動困難（Tardive dyskinesia）一般係由下列那一種原因所造成？
: (A)去極化（Depolarization）所導致邊緣系統（Mesolimbic system）多巴胺（Dopamine
: ）神經元被抑制
: (B)多巴胺受體過度敏感性（Supersensitivity）
: (C)藥物阻斷乙醯膽鹼系統的活性
: (D)阻斷血清素（Serotonin）受體
: 建議答案：A,B
: 佐證資料
: BASIC & CLINICAL PHARMACOLOGY - 10th Ed. (2007)
: Chapter 28.
: Tardive dyskinesia, a disorder characterized by a variety of abnormal
: movements, is a common complication of long-term neuroleptic drug treatment
: (see Chapter 29). "Unfortunately, its precise pharmacologic basis is unclear."
: A reduction in dose of the offending medication, a dopamine receptor blocker,
: commonly worsens the dyskinesia, whereas an increase in dose may suppress it.
: The drugs most likely to provide immediate symptomatic benefit are those
: interfering with dopaminergic function, either by depletion (eg, reserpine,
: tetrabenazine) or receptor blockade (eg, phenothiazines, butyrophenones).
: Paradoxically, the receptor-blocking drugs are the very ones that also cause
: the dyskinesia.
: 其中第三行顯示機轉不明
: 但是可確定的是阻斷dopamine受體的藥物常有此副作用
: 而且B的答案並沒標示清楚是來自何ACh系統
: 所以建議A,B都給分
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