==> bluegene (bluegene) 提到:
> ==> VERITAS.bbs@bbs.tcu.edu.tw (VE RI TAS) 提到:
> > 因為之前許許多多的gene fragment都沒有primer....
> > 還有在作sequence的時候也是挺費時間的。
> > 嗯嗯,可以這麼說啦,就是許多的gene function都不曉得,
> > 而且調控的蛋白質作用也還未完全揭曉呢
^^^^^^^^^^^^^^^^
This is SO wrong... protein control is NOT a part of the
sequencing project. They draft is because sequence is incomplete,
NOT because they don't know the function. Function is not
the central part (if it is in the project at all) of the project
at this point.
> NO! This is a absolutely wrong answer!
> This is not what the "draft of human genome" mean.
> We have so much false information on this board!
> Please refer to the definition of "draft" from HGP's documents.
> It is calle "draft" simply because the sequencing of human genome
> is UNFINISHED! The draft announced recently still contains a lot
> of PHASE 1 and PHASE 2 sequences. PHASE 1 sequences are sequences
> with gaps, uncertain order and orientation. PHASE 2 sequences have
> correct order and orientation but still have gaps.
As i recalled, it is called draft is because this reason,
with ~1% of sequence missing (but it is believe that
most of this 1% do not code for any thing). Also,
there are two versions of draft completed by Celera and
HGP with wide consensus believe the Celera version is the
better version.
One more comment on gene function and protein control,
the rise of the disipline of Computational Biology is because
the determination of protein control and gene function is
even more hacktive than sequencing that biologists turn
to Computational biology instread of the traditional
experimental biology (biochem, MolBio). Thus protein control
and gene function will be part of the disipline of
Computational Biology instead of HGP that concentrate
primarily on the sequence.
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☆ [Origin:椰林風情] [From: JOB.WEH.ANDREW.CMU.EDU] [Login: **] [Post: 93]