[試題] 98上 陳俊宏 普通生物學乙上 期末考 PART1

[shokanshorin (上官薔凜)]

課程名稱︰普通生物學乙上
課程性質︰必修
課程教師︰陳俊宏
開課學院：醫學院
開課系所︰醫學系
考試日期（年月日）︰99／1／14
考試時限（分鐘）：15:30~17:20 (110min)
是否需發放獎勵金：是~
（如未明確表示，則不予發放）

I. Multiple Choices: (30 points, 1 point each)

1. Which of the following reactions use cAMP as secondary messenger in its
   signaling transduction?

   (A) Water reabsorption in collecting duct.
   (B) Visual information processing in human retinal.
   (C) Sweetness detection by sugar receptor in human test buds.
   (D) Progesterone maintaining secretory phase in menstrual cycle.

2. During fertilization, the acrosomal contents

   (A) block polyspermy.
   (B) provide the sperm mitochondria to the egg.
   (C) trigger the completion of meiosis by the sperm.
   (D) digest the protective coat on the surface of the egg.

3. All of the following statements about inflammatory response are correct
   except

   (A) Histamine and acid trigger pain.
   (B) Prostaglandins increase pain by increasing their threshold.
   (C) Mast cells released histamine can dilate nearby blood vessels to
       promote blood flow to the injured site.
   (D) Pyrogens released by activated macrophages or certain toxin produced
       by pathogens set the body thermostat to cause heat.

4. All of the following reactions belong to paracrine signaling except

   (A) Interleukin-Ⅰ secreted from APCs stimulates T_H activation.
   (B) The cells nearest the ZPA give rise to posterior structures.
   (C) The activated T_C release perforin which forms pores in the target
       cell membrane.
   (D) Pre-synaptic nerve cells secret neurotransmitters to affect the
       membrane potential on the post-synaptic cells.

5. All of the following statements about botulinum toxin are correct except

   (A) Botulinum toxin is a food poison from Clostridium botulinum.
   (B) Botulinum toxin can interfere with host's G protein-coupled receptor.
   (C) Botulinum toxin has become a controversial tool for cosmetic procedure.
   (D) Botulinum toxin can block acetylcholine releasing to inhibit muscle
       contraction.

6. The vertical pathway of visual information processing from retina to the
   cerebral cortex is

   (A) pigment cell → photoreceptor cell → ganglion cell → bipolar cell.
   (B) photoreceptor cell → bipolar cell → ganglion cell → pigment cell.
   (C) ganglion cell → photoreceptor cell → bipolar cell → pigment cell.
   (D) pigment cell → photoreceptor cell → bipolar cell → ganglion cell.

7. Which of the following material does not belong to inhibitory neurotrans-
   mitter?

   (A) glycine                          (C) endorphin
   (B) glutamate                        (D) gamma aminobutyric acid

8. If an animal cell lacked the ability to produce GTP, it might

   (A) difficult to synthesize DNA.
   (B) fail to perform cellular respiration.
   (C) cause malfunction on plasma membrane.
   (D) not be able to activate the G protein on the plasma membrane.

9. Equilibrium in humans is not related to

   (A) utricle.                        (C) saccule.
   (B) otolith.                        (D) cochlea.

10. Which of the following tissue is not related to hearing?

    (A) basilar membrane.              (C) tympanic membrane.
    (B) tectorial membrane.            (D) endothelial membrane.

11. Prolactin participates the following life phenomena except

    (A) metamorphosis in frogs.
    (B) mammary gland growth in women.
    (C) fat metabolism and reproduction in birds.
    (D) regulation salt and water balance in salmons.

12. Which of the following statements about tyrosine kinase receptor is
    correct?

    (A) The receptor has seven α-helix transmembrane structure.
    (B) The activated tyrosine kinase receptor can amplify signaling by
        G protein.
    (C) Two receptor molecules join together to form dimer after they bind
        with their ligand.
    (D) The receptor having tyrosine kinase activity can transfer phosphate
        groups from GTP to tyrosine.

13. Which of the following statement about the accessory glands in human male
    reproductive system is incorrect?

    (A) Bartholin's glands secret mucus to facilitating intercourse.
    (B) Prostatic fluid is thin and milky, contains anticoagulant enzyme and
        citrate.
    (C) Bulbourethral glands secret clear mucus to neutralize acidic urine
        remaining in the urethra.
    (D) The floid from the seminal vesicles contains mucus, ascorbic acids,
        fructose, a coagulating enzyme, and prostaglandings.

14. Once embryonic cells differ from each other, the cells begin to influence
    each other's fates by induction. Which of the following is not the case of
    induction?

    (A) During gastrulation, blastula cells detach from vegetal pole and enter
        blastocoel to form mesenchyme cells.
    (B) Apical ectodermal ridge is required for the outgrowth of the limb
        along the proximal-distal axis.
    (C) BMP-4 is acitve exclusively in the cells on the ventral side of
        embryo, and the dorsal site of the embryo produce inhibitor to
        bind with BMP-4.
    (D) The len cells receive signals from neural plate cells and the optic
        cup.

15. The identical twins lived in different cities show obviously different
    immuno-responses due to different
    (A) clonal selection.              (C) immunological memory.
    (B) self-tolerance                 (D) immunoglobulin gene rearrangement.

16. A normal embryogenesis includes the following process except

    (A) differentiation.               (C) morphogenesis
    (B) parthenogenesis.               (D) pattern formation.

17. What is the typical osmolarity of human blood?
    (A) 100 mosm/L                     (C) 300 mosm/L
    (B) 200 nosm/L                     (D) 500 mosm/L

18. The following pairing reproductive structures have similar functions
    except

    (A) clitoris - glans penis         (C) corpus luteum - Leydig cells
    (B) oviduct - vas deferens         (D) penis - vagina

19. Which of the following statement about menstrual cycle is incorrect?

    (A) It specifically occurs in the endometrium of the uterus.
    (B) It is divided into menstrual flow phase, proliferative phase, and
        secretory phase.
    (C) The cycle length is about 28 days, and varies from one woman to
        another.
    (D) It is regulated by FSH and LH, and continues from puberty to death.

20. Which of the following statements about bioenergetics is true?

    (A) Endotherms are mainly warmed by metabolic hear.
    (B) A BMR can be determined only at a specific temperature.
    (C) An SMR is best measured just after an ectoderm has eaten.
    (D) Every animal has a specific metabolic rate that does not change.

21. The correct sequence of human intesine is
    (A) duodenum → ileum → jejunum → colon → cecum → rectum.
    (B) duodenum → jejunum → ileum → colon → cecum → rectum.
    (C) duodenum → jejunum → colon → ileum → cecum → rectum.
    (D) duodenum → jejunum → ileum → cecum → colon → rectum.

22. How does connective tissue differ from the other three major tissue types?

    (A) Connective tissue is found lining body surfaces.
    (B) Connective tissue consists of contractile proteins.
    (C) Connective tissue consists of cells capable of transmitting electrical
        impulse.
    (D) Connective tissue often consists of relatively few cells embedded in
        an extracellular matrix.

23. When cells meet either higher or lower temperature challenge, they may
    (A) increase their size by uptake more water.
    (B) decrease the amount of membrane proteins.
    (C) synthesize new stress proteins as cryoprotectant.
    (D) change proportions of saturated and unsaturated lipids on memebranes.

24. When a human's large intestine occurs malfunction, he might show
    (A) Diarrhea or constipation.      (C) Reingestion or constipation.
    (B) Diarrhea or appendicitis.      (D) Reingestion or appendicitis.

25. The sequence of development proceeds as

    (A) cleavage → blastula → gastrula → morula.
    (B) cleavage → morula → blastula → gastrula.
    (C) gastrula → morula → blastula → cleavage.
    (D) morula → blastula → gastrula → cleavage.

26. Which of the following is not the cardiovascular disease in human?

    (A) angina pectoris.               (C) anorexia nervosa.
    (B) atherosclerosis.               (D) myocardial infarction.

27. What happens when the CO2 level from cellular respiration increases in
    blood?

    (A) The O2 level automatically increases and cellular respiration
        decreases.
    (B) The pH of the cerebrospinal fluid also increases and is detected by
        O2 sensors in arteries near the heart.
    (C) The medulla, moderated by the pons, signals the heart muscle to beat
        harder, bringing in more O2.
    (D) A decrease in the pH of the cerebrospinal fluid triggers the brain's
        breathing control centers, which stimulate diaphgram and rib muscle
        contractions.

28. Which of the following might make the most effective anti-ulcer
    medication?

    (A) a chemical that kills bacteria in the stomach.
    (B) a chemical that stimulates the secretion of bile.
    (C) a chemical that inhibits the secretion of chief cells.
    (D) a chemical that increase mucus secretion in the stomach.

29. Which of the following is not related to renin-angiotensin-aldosterone
    system?

    (A) glomerulus.                    (C) juxtaglomerular apparatus.
    (B) adrenal glands .               (D) vascular endothelium in the lungs.

30. The  following events occur when a mammalian immune system first
    encounters a pahtogen.
    Ⅰ.pathogen is destroyed.          Ⅱ.lymphocytes secrete antibodies.
    Ⅲ.antigenic determinanats from pathogen bind to antigen receptors on
       lymphocytes.
    Ⅳ.lymphocytes specific to antigenic determinants from pathogen become
       numerous.
    Ⅴ.only memory cells remain.
    The correct sequence is

    (A)Ⅲ-Ⅱ-Ⅰ-Ⅴ-Ⅳ                      (C)Ⅲ-Ⅳ-Ⅱ-Ⅰ-Ⅴ
    (B)Ⅲ-Ⅰ-Ⅱ-Ⅳ-Ⅴ                      (D)Ⅲ-Ⅳ-Ⅴ-Ⅱ-Ⅰ

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