課程名稱︰風險危害評估
課程性質︰領域必修
課程教師︰吳章甫/吳焜裕
開課學院：公衛學院
開課系所︰公衛學系
考試日期（年月日）︰101.11.02
考試時限（分鐘）：100
是否需發放獎勵金：是
（如未明確表示，則不予發放）
試題 :
1. (1) What is the definition of risk assessment?
(2) What are the four steps of risk assessment process?
(15%)
2."Short-term" test is one of the methods for the hazard identification.
Please give the example how it is conducted. (10%)
3. What is the relationship between NOAEL and Reference dose?
What are the major limitations or criticisms of using NOAEL to derive
Reference dose? (15%)
4. What are the two extrapolation models in dose-response assessment?
5. Give three methods that are commonly used to quantify the exposures? (10%)
6. What are the differences between intake and uptake? (10%)
7. What is Monte Carlo analysis and what are the major steps to perform such
an analysis? (10%)
8. What is "source-receptor model"? Please also explain its importance and
usefulness in investigating issues of environmental health. (10%)
9. You have seen such a figure below during a class. Please comment on what
you observe in this figure in terms of risk characterization. (15%)
Nearby Resident Population
Excess Lifetime Cancer Risk ≦0.0003
0.01｜
｜ Public water supply Contaminated fish
0.001｜ (0.0002) (0.0001)
｜ ▅ ▅
0.0001｜ ▇ ▇
｜ ▇ ▇
0.00001｜ ▇ (0.000007) ▇
｜ ▇ ▆ ▇
0.000001｜ ▇ ▇ ▇
｜ ▇ ▇ ▇
0.0000001｜＿ ▇＿＿＿＿＿ ▇＿＿＿＿＿＿＿＿＿＿＿＿＿▇＿＿＿＿
▇: Chlordane x-axis: exposure pathway
▇: Benzene y-axis: upper-bound excess
lifetime cancer risk
--
※ 發信站: 批踢踢實業坊(ptt.cc)
◆ From: 140.112.213.241