精華區beta NTU-Exam 關於我們 聯絡資訊
課程名稱︰普通生物學乙上 課程性質︰必修 課程教師︰陳俊宏 開課學院:醫學院 開課系所︰醫學系 考試日期(年月日)︰2008/10/27 考試時限(分鐘):110min 是否需發放獎勵金:是 (如未明確表示,則不予發放) Ⅰ. Choice Part A: Simple Choice (one point for each) 1. If a modern electron microscope (TEM) can resolve biological images to the nanometer level, as opposed to the best light microscope, this is due to which of the following? A. The focal length of the electron microscope is significantly longer. B. Contrast is enhanced by staining with atoms of heavy metal. C. Electron beams have much shorter wavelengths than visible light. D. The electron microscope has much greater ratio of image size to real size. E. The electron microscope cannot image whole cells at one time. 2. All of the following are part of a prokaryotic cell except A. DNA. B. a cell wall. C. a plasma membrane. D. ribosomes. E. an endoplasmic reticulum. 3. The volume enclosed by the plasma membrane of plant cells is often much larger than the corresponding volume in animal cells. The most reasonable explanation for this observation is that A. plant cells are capable of having a much higher surface-to-volume ratio than animal cells. B. plant cells have a much more highly convoluted (folded) plasma membrane than animal cells. C. plant cells contain a large vacuole that reduces the volume of the cytoplasm. D. animal cells are more spherical, while plant cells are elongated. E. the basic functions of plant cells are very different from those of animal cells. 4. Which type of organelle is primarily involved in the synthesis of oils, phospholipids, and steroids? A. ribosome. B. lysosome. C. contractile vacuole. D. smooth endoplasmic reticulum. E. mitochondrion. 5. The Golgi apparatus has a polarity or sidedness to its structure and function. Which of the following statements correctly describes this polarity? A. Transport vesicles fuse with one side of the Golgi and leave from the opposite side. B. Proteins in the membrane of the Golgi may be sorted and modified as they move from one side of the Golgi to the other. C. Lipids in the membrane of the Golgi may be sorted and modified as they move from one side of the Golgi to the other. D. Soluble proteins in the cisternae (interior) of the Golgi may be sorted and modified as they move from one side of the Golgi to the other. E. All of the above correctly describe polar characteristics of the Golgi function. 6. Tay-Sachs disease is a human genetic abnormality that results in cells accumulating and becoming clogged with very large and complex lipids. Which cellular organelle must be involved in this condition? A. the endoplasmic reticulum. B. the Golgi apparatus. C. mitochondrion. D. the lysosome. E. membrane-bound ribosomes. 7. The mitochondrion, like the nucleus, has two or more emebrane layers. How is the innermost of these layers different from that of the nucleus? A. The inner mitochondrial membrane is highly folded. B. The two membranes are biochemically very different. C. The space between the two layers of the nuclear membrane is larger. D. The inner membrane of the mitochondrion is separated out into thylakoids. E. The inner mitochondrial membrane is devoid of nearly all proteins. 8. Microfilaments are well-known for their role in which of the following? A. ameboid movement. B. formation of cleavage furrows. C. contracting of muscle cells. D. A and B only. E. A, B, and C. 9. A cell lacking the ability to make and secrete glycoproteins would most likely be deficient in its A. nuclear DNA. B. extracellular matrix. C. Golgi apparatus. D. A and B only. E. A, B, and C. 10. Recent evidence shows that the extracellular matrix can take part in regulating the expression of genes. A likely possibility for this might be which of the following? A. Mechanical signals of the ECM can alter the cytoskeleton, which can alter intracellular signaling. B. Intracellular signals might cause changes in the fibronectin binding to the cell surface. C. Orientation of microfilaments to the ECM can change the gene activity. D. Fibronectin binds to integrins built into the plasma membrane. E. Proteoglycans in the ECM become large enough in aggregate to force genetic alternation. 11. Cells of the pancreas will incorporate radioactively labeled amino acids into proteins. This "tagging" of newly synthesized proteins enables a researcher to track their location. In this case, we are tracking an enzyme secreted by pancreatic cells. What is its most likely pathway? A. ER → Golgi → mucleus. B. Golgi → ER → lysosome. C. nucleus → ER → Golgi. D. ER → Golgi → vesicles that fuse with plasma membrane. E. ER → lysosome → vesicles that fuse with plasma membrane. 12. Who proposed that the membrane is a mosiac of protein molecules bobbing in fluid bilayer of phospholipids? A. H. Davson and J. Danelli. B. I. Langmuir. C. E. Gorter and F. Grendel. D. S. Singer and G. Nicolson. E. C. Overton. 13. When biological membranes are frozen and then fractured, they tend to break along the middle of the bilayer. The best explanation for this is that A. the integral membrane proteins are nto strong enough to hold the bilayer together. B. water that is present in the middle of the bilayer freezes and is easily fractured. C. the hydrophobic interactions that hold the membrane together are weakest at this point. D. hydrophilic interactions between the opposite membrane surfaces are destroyed on freezing. E. the carbon-carbon bonds of the phospholipids tails are easily broken. 14. Cell emebranes are asymmetrical. Which of the following is a most likely explanation? A. The cell membrane forms a border between one cell and another in tightly packed tissues such as epithelium. B. Cell membranes communicate sgnals from one organism to another. C. Cell membrane proteins are determined as the membrane is being packaged in the ER and Golgi. D. Cell membrane proteins are determined as the membrane is baing packaged in the ER and Golgi. (all the same as C = =a) E. Proteins can only span cell membranes if they are hydrophobic. 15. Celery stalks (美國芹菜) that are immersed in fresh water for several hours become stiff and har. Similar stalks left in a salt solution become limp and soft. From this we can deduce that the cells of the celery stalks are A. hypertonic to fresh water but hypotonic to the salt solution. B. hypotonic to both fresh water and the salt solution. C. hypertonic to both fresh water and the salt solution. D. isotonic with fresh water but hypotonic to the salt solution. E. hypotonic to fresh water but hypertonic to the salt solution. 16. If a membrane protein in an animal cell is involved in the cotransport of glucose and sodium ions into the cell, which of the following is most likely true? A. A substance that blocked sodium ions from binding to the cotransport protein would also block the transport of glucose. B. Potassium ions move across the same gradient as sodium ions. C. Sodium ions can move down their electrochemical gradient through the cotransporter whether or not glucose is present outside the cell. D. The sodium ions are moving down their electrochemical gradient while glucose is moving up. E. Glucose is entering the cell along its concentration gradient. 17. What term is used to describe the transfer of free energy from catabolic pathways to anabolic pathways? A. feedback inhibition. B. bioenergetics. C. energy coupling. D. entropy. E. cooperativity. 18. The mechanism in which the end product of a metabolic pathway inhibits an earlier step in the pathway is known as A. metabolic inhibition. B. feedback inhibition. C. allosteric inhibition. D. noncooperative inhibition. E. reversible inhibition. 19. The molecule that functions as the reducing agent (electron donor) in a redox or oxidation-reduction reaction A. gains electrons and gains energy. B. loses electrons and loses energy. C. gains electrons and loses energy. D. loses electrons and gains energy. E. neither gains nor loses electrons, nor gains or loses energy. 20. Which process in eukaryotic cells will proceed normally whether oxygen (O2) is present or absent? A. electron transport. B. glycolysis. C. citric acid cycle. D. chemiosmosis. E. fermentation. -- 35P淚目 -- 美國芹菜... (腦補) 法國香菜(踹飛) -- ※ 發信站: 批踢踢實業坊(ptt.cc) ◆ From: 114.40.170.165 ※ 編輯: shokanshorin 來自: 114.40.170.165 (07/08 10:03)
liltwnboiz :35................你怎麼打的.................... 07/08 12:24
ALegmontnick:done 07/08 15:45
> -------------------------------------------------------------------------- < 作者: shokanshorin (上官薔凜) 看板: NTU-Exam 標題: [試題] 97上 陳俊宏 普通生物學乙上 第一次期中考 Part2 時間: Sun Jul 10 11:57:27 2011 課程名稱︰普通生物學乙上 課程性質︰必修 課程教師︰陳俊宏 開課學院:醫學院 開課系所︰醫學系 考試日期(年月日)︰2008/10/27 考試時限(分鐘):110min 是否需發放獎勵金:是 (如未明確表示,則不予發放) 21. Which of the following intermediary metabolites enters the citric acid cycle and is formed, in part, by the removal of a carbon dioxide (CO2) from one molecule of pyruvate? A. alcohol. B. lactate. C. glyceraldehydes-3-phosphate. D. acetyl-CoA. E. citrate. 22. During aerobic respiration, electrons travel downhill in which sequence? A. food → NADH → electron transport chain → oxygen. B. food → citric acid cycle → ATP → NAD+. C. glucose → pyruvate → ATP → oxygen. D. food →glycolysis → citric acid cycle → NADH → ATP. E. glucose → ATP → electron transport chain → NADH. 23. What is proton-motive force? A. The force required to remove an electron from hydrogen. B. Movement of hydrogen into the mitochondrion. C. The transmembrane proton concentration gradient. D. The addition of hydrogen to NAD+. E. The transmembrane proton concentration gradient. (the same as C) 24. Which of the following describes ubiquinone? A. A small hydrophobic electron carrier. B. A protein in the electron transport chain. C. A substrate for synthesis of FADH2. D. An essential amino acid. E. A vitamin needed for efficient glycolysis. 25. In alcohol fermentation, NAD+ is regenerated from NADH during which of the following? A. reduction of pyruvate to form lactate. B. oxidation of NAD+ in the citric acid cycle. C. phosphorylation of ADP to form ATP. D. reduction of pyruvate to PEP. E. reduction of acetaldehyde to ethanol. (ethyl alcohol) 26. Phosphofructokinase is an important control enzyme in the regulation of cellular respiration. Which of the following statements describes a function of phosphofructokinase? A. It is an allosteric enzyme. B. It is activated by ATP. C. It is inhibited by AMP. D. It catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate, an early step of glycolysis. E. It is inhibited by citrate, an intermediate of the citric acid cycle. 27. In vertebrate animals, brwon fat tissue's color is due to abundant contains relatively few mitochondria. Brown fat cells have a specialized protein that dissipates the proton-motive force across the mitochondrial membranes. Which of the following might be the function fo the brown fat tissue? A. to increase the production of ATP synthase. B. to increase the rate of oxidative phosphorylation from its few mitochondria. C. to allow the animals to regulate their metabolic rate when it is especially hot. D. to regulate temperature by converting energy from NADH oxidation to heat. E. to allow other membranes of the cell to perform mitochondrial function. 28. Which of the following are directly associated with photosystem Ⅰ? A. P680 reaction-center chlorophyll. B. harvesting of light energy by ATP. C. passing electrons to plastoquinone. D. receiving electrons from plastocyanin. E. extraction of hydrogen electrons from the splitting of water. 29. In mitochondria, chemiosmosis translocates protons from the matrix into the intermembrane space, whereas in chloroplasts, chmiosmosis translocates protons from A. the stroma to the thylakoid space. B. the matrix to the stroma. C. the stroma to the photosystem Ⅱ. D. the intermembrane space to the matrix. E. ATP synthase to NADP+ reductase. 30. Why are C4 plants able to photosynthesize with no apparent photorespiration? A. They do not participate in the Calvin cycle. B. They use PEP carboxylase to initially fix CO2. C. They are adapted to cold, wet climates. D. They conserve water more efficiently. E. They exclude oxygen from their tissues. 31. CAM plants keep stomata closed in daytime, thus reducing loss of water. They can do this because they A. fix CO2 into pyruvate in the mesophyll cells. B. fix CO2 into sugars in the bundle-sheath cells. C. fix CO2 into organic acids during the night. D. use the enzyme phosphofructokinase, which outcompetes rubisco for CO2. E. use photosystems Ⅰ and Ⅱ at night. 32. Vinblastine is a standard chmotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to A. disruption of mitotic spindle formation. B. inhibition of regulaorty protein phosphorylation. C. myosin denaturation and inhibition of cleavage furrow formation. D. inhibition of DNA synthesis. E. suppression of cyclin production. 33. Cells from an advanced malignant tumor most often have very abnormal chromosomes, and often an abnormal total number of chromosomes. Why might this occur? A. Chromosomally abnormal cells still have normal metabolism. B. Transformation introduces new chromosomes into cells. C. Cancer cells are no longer density dependent. D. Cancer cells are no longer anchorage dependent. E. Chromosomally abnormal cells can still go through cell cycle checkpoints. 34. Which of the following describe(s) cyclin-dependent kinase (Cdk) ? A. Cdk is present throughout the cell cycle. B. Cdk is inactive, or "turned off," in the presence of cyclin. C. Cdk is an enzyme that attaches phosphate groups to other proteins. D. Both A and C are true. E. Both B and C are true. 35. The MPF protein complex turns itself off by A. activating a process that destroys cyclin component. B. activating an enzyme that stimulates cyclin. C. binding to chromatin. D. exiting the cell. E. activating the anaphase-promoting complex. 36. Which phase of the cell cycle is shortest? A. G0. B. G1. C. S. D. G2. E. M. -- ※ 發信站: 批踢踢實業坊(ptt.cc) ◆ From: 114.40.173.192
ALegmontnick:done 07/10 14:25
> -------------------------------------------------------------------------- < 作者: shokanshorin (上官薔凜) 看板: NTU-Exam 標題: [試題] 97上 陳俊宏 普通生物學乙上 第一次期中考 Part3 時間: Sun Jul 10 14:14:42 2011 課程名稱︰普通生物學乙上 課程性質︰必修 課程教師︰陳俊宏 開課學院:醫學院 開課系所︰醫學系 考試日期(年月日)︰2008/10/27 考試時限(分鐘):110min 是否需發放獎勵金:是 (如未明確表示,則不予發放) Part B. Multiple choice (2 points * 20) 1. Replication in prokaryotes differs from replication in eukaryotes for which of these reasons? A. The prokaryotic chromosome has histones, whereas eukaryotic chromosomes do not. B. Prokaryotic chromosomes have a single origin of replication, whereas eukaryotic chromosomes have many. C. The rate of elongation during DNA replication is slower in prokaryotes than in eukaryotes. D. Prokaryotes produce Okazaki fragments during DNA replication, but eukaryotes do not. E. Prokaryotes have telomeres, and eukaryotes do not. 2. What is meant by the description "antiparallel" regarding the strands that make up DNA? A. The twisting narute of NDA creates nonparallel strands. B. The 5' to 3' direction of one strand runs counter to the 5' to 3' direction of the other strand. C. Base pairings create unequal spacing between the two DNA strands. D. One strand is positively charged and the other is negatively charged. E. One strand contains only purines and the other contains only pyrimidines. 3. To repair a thymine dimer by nucleotide excision repair, in which order do the necessary enzymes act? A. exonuclease, DNA polymerase Ⅲ, RNA primase. B. helicase, DNA polymerase Ⅰ, DNA ligase. C. DNA ligase, nuclease, helicase. D. DNA polymerase Ⅰ, DNA polymerase Ⅲ, DNA ligase. E. endonuclease, DNA polymerase Ⅰ, DNA ligase. 4. Which would you expect of a eukaryotic cell lacking telomerase? A. a high probability of becoming cancerous. B. production of Okazaki fragments. C. inability to repair thymine dimers. D. a reduction in chromosome length. E. high sensitivity to sunlight. 5. Which of the following statements is TRUE of chromatin? A. Heterochromatin is composed of DNA, whereas euchromatin is made of DNA and RNA. B. Both heterochromatin and euchromatin are found in the cytoplasm. C. Heterochromatin is highly condensed, whereas euchromatin is less compact. D. Euchromatin is not transcribed, whereas heterochromatin is transcribed. E. Only euchromatin is visible under the light microscope. 6. The genetic code is essentially the same for all organisms. From this, one can logically assume all of the following EXCEPT A. A gene from an organism could theoretically be expressed by any other organism. B. All organisms have a common ancestor. C. DNA was the first genetic material. D. The same codons in different organisms usually translate into the same amino acids. E. Different organisms have the same number of different types of amino acids. 7. Which of the following is TRUE for both prokaryotic and eukaryotic gene expression? A. After transcription, a 3' poly-A tail and a 5' cap are added to mRNA. B. Translation of mRNA can begin before transcription is complete. C. RNA polymerase binds to the promoter region to begin transcription. D. mRNA is synthesized in the 3' → 5' direction. E. The mRNA transcript is the exact complement of the gene from which it was copied. 8. Transcription in eukaryotes requires which of the following in addition to RNA polymerase? A. the protein product of the promoter. B. start and stop codons. C. ribosomes and tRNA. D. several transcription factors. (TFs) E. aminoacyl synthetase. 9. Chosse the answer that has these events of protein synthesis in the proper sequence. 1. An aminoacyL-tRNA binds to the A site. 2. A peptide bond forms between the new amino acid and a polypeptide chain. 3. tRNA leaves the P site, and the P site remains vacant. 4. A small ribosomal subunit binds with mRNA. 5. tRNA translocates to the P site. A. 1,3,2,4,5 B. 4,1,2,5,3 C. 5,4,3,2,1 D. 4,1,3,2,5 E. 2,4,5,1,3 10. Which of the following DNA mutations is the most likely to be damaging to the protein it specifies? A. a base-pair deletion. B. a codon substitution. C. a substitution in the last base of a codon. D. a codon deletion. E. a point mutation. 11. Of the following, which is the most current description of a gene? A. a unit of heredity that causes formation of a phenotypic characteristic. B. a DNA subunit that codes for a single complete protein. C. a DNA sequence that is expressed to form a functional product: either RNA or polypeptide. D. a DNA-RNA sequence combination that results in an enzymatic product. E. a discrete unit of hereditary information that consists of a sequence of amino acids. 12. Altering patterns of gene expression in prokaryotes would most likely serve the organism's survival in which of the following ways? A. organzing gene expression so that genes are expressed in a given order. B. allowing each gene to be expressed an equal number of times. C. allowing the organism to adjust to changes in environmental conditions. D. allowing young organisms to respond differently from more mature organisms. E. allowing environmental changes to alter the prokaryotes's genome. 13. Genomic imprinting, DNA methylation, and histone acetylation are all examples of A. genetic mutation. B. chromosomal rearrangements. C. karyotypes. D. epigenetic phenomena. E. translocation. 14. Approximately what proportion of the DNA in the human genome codes for proteins or functional RNA? A. 83% B. 46% C. 32% D. 13% E, 1.5% 15. In eukaryotes, general transcription factors A. are required for the expression of specific protein-encoding genes. B. bind to other proteins or to a sequence element within the promoter called the TATA box. C. inhibit RNA polymerase binding to the promoter and begin transcribing. D. usually lead to a high level of transcription even without additional SPECIFIC transcription factors. E. bind to sequence just after the start site of transcription. 16. The incidence of cancer increases dramatically in older humans because A. The Ras protein is more likely to be hyperactive after age sixty. B. Proteasomes become more active with age. C. As we age, normal cell division inhibitors cease to functino. D. The longer we live, the more mutations we accumulate. E. Tumor-suppressor genes are no longer able to repair damaged DNA. 17. Which of the following seems to be the known upper and lower size limits of genomes? A. 1 ~ 2900 Mb. (million base pairs) B. 1,500 ~ 40,000 Mb. C. 1 ~ 580,000 Mb. D. 100 ~ 120,000 Mb. E. 100 ~ 200,000 Mb. 18. Which of the following is a major distinction between a transposon and a retrotransposon? A. A transposon always leaves a copy of itself at its original position and a retrotransposon does not. B. A retrotransposon always uses the copy-paste mechanism, while a transposon uses cut and paste mechanism. C. A transposon is related to a virus and a retrotransposon is not. D. A transposon moves via a DNA intermediate and a retrotransposon via an RNA intermediate. E. The positioning of a transposon copy is transient while that of a retrotransposon is permanent. 19. Bioinformatics includes all of the following EXCEPT A. using computer programs to align DNA sequences. B. analyzing protein interactions in a species. C. using molecular biology to provide biological information to a system so that it gets expressed. D. development of computer-based tools for genome analysis. E. use of mathematical tools to make sense of bioological systems. 20. Two eukaryotic proteins have one domain in common but are otherwise very different. Which of the following processes is most likely to have contributed to this phenomenon? A. gene duplication. B. RNA splicing. C. exon shuffling. D. histone modification. E. random point mutations. Ⅲ. Give a proper word or statement in the blank. (one point for each) 1. The reaction center of Photosystem Ⅰ and system Ⅱ in chloroplasts are ____________________ and ____________________, respectively. The molecular oxygen is generated by ____________________. (which photosystem) 2. Higher plants posses several types of photosynthesis-related pigments. ____________________ is essential for photochemical reactions, and others are accessory pigments: ____________________ and ____________________. 3. The Calvin cycles has three phases: (i) CO2 fixation, catalyzed by ____________________, the most abundant leaf protein; (ii) ____________________ __________ __________ ____________________. (a method) (iii) ____________________________________________________________________. (the next method) 4. CO is a respiratory inhibitor that blocks ____________________ (which step) respiration. 5. The major functions of cellular respiration are: ____________________ and ____________________. 6. ____________________ (a protein complex) located in inner mitochondrial membrane couples the electron transport process and ATP production. 7. The products of linear electron transport of photosynthesis are ____________________ and ____________________. 8. How many reduced dinucleotides can be produced while the Calvin cycle runs two turns: __________ FADH2, __________ NADH and __________ NADPH. (Fill in numbers) 9. The sodium-potassium pump is called an electrogenic pump because it pumps __________ Na+ out and __________ K+ at the expense of one ATP. (Fill in numbers) 10. All the DNA in a cell constitutes the cell's ____________________. 11. When a cell is dividing, two chromatids are separated after metaphase because ____________________ is split and chromosomes move toward the poles of the spindle because the microtubular fiber attached is shortened to by depolymerization at the ____________________ ends. 12. Plasmodesmata in plant tissues are most similar in function to ____________________ of animal cells. (a structure of cellular connections) -- 剛剛有個GPA快4的死小孩丟水球給我 結果家裡的網路太不爽他了 就給我瞬斷瞬連... 這篇如果沒1000p的話含發放獎勵金都要他賠~~(口桀口桀) -- ※ 發信站: 批踢踢實業坊(ptt.cc) ◆ From: 114.40.173.192
shokanshorin:451P...TC你完蛋了 07/10 14:14
※ 編輯: shokanshorin 來自: 114.40.173.192 (07/10 14:15)
ALegmontnick:done 07/10 14:25