Re: [申覆] 醫學(六) 54

[mercury99986 (汪汪)]

Novak 13e

5a-Reductase Deficiency 5a-Reductase deficiency should also be considered as a
cause of amenorrhea ( 21). Patients with this disorder are genotypically XY,
frequently experience virilization at puberty, have testes (because of
functioning Y chromosomes), and have no mullerian structures due to functioning
mullerian-inhibiting factor (MIF). 5a-Reductase converts testosterone to its
more potent form, dihydrotestosterone........Normal male differentiation of
the urogenital sinus and external genitalia do not occur, because
dihydrotestosterone is required for this development. However, normal internal
male genitalia derived from the Wolffian ducts are present because this
development requires only testosterone.

由此可知病患為正常46 XY染色體,為男性假性陰陽人(male pseudohermaphroditism)
所以選項中四個敘述均描述此病患為女性,與醫學上的判定有Y染色體即為
男性的事實不符合,因此選項描述錯誤造成考生誤解,建議應一律送分


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