推 trees880098 : 收心理系 01/16 12:09
課程名稱︰生理心理學
課程性質︰必修
課程教師︰賴文崧
開課學院：理學院
開課系所︰心理學系
考試日期（年月日）︰2014/11/17
考試時限（分鐘）：3小時
是否需發放獎勵金：是
試題 :
第一大題：配合題（每題1分共42分）
I.Please match the following techniques and descriptions
to answer question #1-10.
Techniques decriptions
─────-────────┬────────────────────────
1. CT │(A) detecting an immediate early gene expression
2. PET │ in cells or neurons
3. fMRI │(B) stimulation of cortical neurons through the
4. MEG │ application of strong magnetic fields
5. TMS │(C) using specific antibody-antigen binding to
6. Optical imaging │ detect a particular protein in tissues
7. in situ hybridization │(D) examining brain function by injecting
8. Immunocytochemistry │ radioactive subtance
9. c-Fos immunostaining │(E) showing the distribution of radioactive
10. autoradiography │ chemicals in tissues
│(F) examining brain structure by X-Rays
│(G) measures the tiny magnetic fields produced
│ by active neurons in the brain
│(H) detecting particular RNA transcript
ans. │ in tissues
FDIGBJHCAE │(I) identifying brain regions that are
│ particularly active during given task by
│ detecting changes in blood flow
│(J) visualizing brain activity by near-infrared
│ light
─────-────────┴────────────────────────
II. Please answer the following question(#11-17) regarding Fugure 1.
Figure 1.(示意圖不夠精美請海涵，建議參考課本圖)
50↑---------------------------
│ ┌-┐
30│--------┼-┼--------------
│ │ │
│ │ │
0│--------┼-┼--------------
mV │ │ │
│ │ │
-40│----┌─┘-│--------------
│ │ │
-60├──┘-----│--┌─────
│ └─┘
└──┴─┴-┴─┴──┴───→
１ ２ ３ ４ ５
(A)Na+ (B)K+ (C)Relative (D)Absolute (E)Resting potential (F)Threshold
(G)Depolarization (H)Repolarization (I)Action potential
1. In phase 1, open K+ channel creates the __(11)__ (-60mV).
2. In phase 2, sufficient __(12)__ of the axon results in a/an __(13)__.
3. In phase 3, the __(14)__ refractory period,
voltage-gated __(15)__channels open,
causing a rapid change of polarity.
4. In phase 4, open gated __(16)__ channels cause __(17)__.
Ans. EGIDABH
─────-────────────────────────────────
III. Please match each of the following statements(#18-21)
with its relevant hypothesis
__(18)__: Primates show a correlation between clique size and
size of the cortex relative to overall brain size.
__(19)__: The tail of the male peacock(of the peafowl species)is energy
demanding; therefore, it must confer some food gathering advantage.
__(20)__: is intended to explain two different phenomena:
the advantage of sexual reproduction at the level of individuals,
and the constant evolutionary arms race between competing species.
__(21)__: individual's learning behavior could bring alternative in
population evolution.
A. Red queen hypothesis B. Bottleneck effect C. Handicap principle
D. Social brain hypothesis E. Baldwin effect
ans.DCAE
IV. Please match each of the following statement(#22-30)with a relevant type
of hormones
─────-─────────────────-┬──────────────
__(22)__ 1. Cretinism │A. Thyroid hormone
__(23)__ 2. Aggression │B. Trisomy chromisome 21
__(24)__ 3. the 3rd eye:photosensitive cell │C. Vasopressin
__(25)__ 4. Pair-bonding in male prairie voles│D. Testosterone
__(26)__ 5. Milk letdown reflex │E. Melatonin
__(27)__ 6. Reduce inflammation │F. Glucocorticoids
__(28)__ 7. Typical antipsychotics │G. Oxytocin
__(29)__ 8. Alzheimer's disease │H. Acetylcholine
__(30)__ 9. Down syndrome │I. Dopamine
│J. Nicotinic receptors
ans.ADECGFIHB │K. Growth hormone
─────-────────────────-─┴──────────────
V.Please match each of the following statements(#31-34)
with its relevant effect
__(31)__: The more older brothers a boy has, the more likely he is to grow up
to be gay.
__(32)__: a permanent alteration of the nervous system, and thus permanent
change in behavior, resulting from the action of a steroid hormone
on an animal early in its development.
__(33)__: is a phenomenon seen in mammalian species whereby males(and to a
lesser extent females)exhibit renewed sexual interest if introduced
to new receptive sexual partners.
__(34)__: refers to the tendency for female rodents to terminate
their pregnancies following exposure to the scent of an unfamiliar
male.
A. The Coolidge Effect B. Bruce effect(pregnancy block effect)
C. Lee-Boot Effects D. Whitten effect E. Fraternal birth order effect
F. Activation effect G. organizational effect
ans.EGAB
VI. Please match each of the following terms or psychopharmacological drugs
(#35-42)with a relevant receptor type or ion channel
─────-──────────────-┬─────────────────
__(35)__. Curare │A. GABA receptors
__(36)__. Tetrodotoxin(TTX) │B. Acetylcholine receptors
__(37)__. G protein │C. Dopaminergic receptors
__(38)__. Prozac │D. Serotonin receptors
__(39)__. Marijuana │E. Opioid receptors
__(40)__. Heroin │F. Cannabinoid receptors
__(41)__. Amphetamine │G. Glutamatergic receptors
__(42)__. Phencyclidine(PCP) │H. metabotropic receptors
ans.BIHDFECG │I. Sodium channels
──-────────────────-─┴─────────────────
第二大題：名詞解釋：20題，每題2分，共40分
1. Diffusion tensor imaging (DTI)
2. Blood-brain carrier
3. Neural tube
4. Amyotrophic lateral sclerosis (ALS)
5. Excitatory postsynaptic potential (EPSP)
6. Conditional knockout mice
7. Agonist/antagonist
8. Salutatory conduction
9. Ecological niche
10. Encephalization factor
11. Single-nucleotide polymorphisms (SNPs)
12. Orgasm
13. SRY gene
14. HPA axis
15. Anosmia
16. Major histocompatibility complex (MHC)
17. Neurotrophic factors
18. Lodosis
19. Dose-response curve (DRC)
20. Down-regulation versus up-regulation
第三大題：簡答申論題：4題，每題7分，共28分
1. 請論述神經傳導物質與激素的作用機制，並比較兩者間的相似與相異之處。
2. 請描述神經突觸的型態和功能。
並且根據下圖，詳述並解釋synaptic transmission的步驟。
（請參考Biological Psychology課本中第3章前後突觸之間的反應圖）
3. 請根據課本說明神經系統發展過程中的幾個關鍵步驟，
並分別描述及說明每個步驟 的細節與目的。
4.說明何謂trinucleotide repeats? 請以課本所教授過的相關神經疾病中舉一個實例，
說明這個疾患的症狀以及可能的致病機轉。
滿分共110分
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