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原文標題: Moderna Warns New Waves of Covid-19 Are Coming Moderna 警告新一波 Covid-19 即將到來 原文連結: https://reurl.cc/zezERy 發布時間: Updated May 28, 2021 9:03 am ET / Original May 28, 2021 8:17 am ET 原文內容: Moderna scientists and executives laid out their plans to combat new strains of the virus that causes Covid-19 at a virtual investor event on Thursday, saying that new waves of the epidemic are on their way. “As the virus spreads, it is rapidly mutating,” the company’s chief scientific officer, Melissa Moore, said on the call. “Some of these new viral strains appear to be even more transmissible than the original strain… We already know that some of these new strains are less susceptible to neutralization by our current vaccine.” The company said that it tests new variants in the lab against its vaccines, and is “constantly” making and testing new versions of its vaccine. But it warned that the process is not instantaneous, and that the company’s agility is limited by the complexity of the work. “The shortest time from the detection of a variant of concern to preclinical immunogenicity readout against a panel of pseudoviruses is approximately 2 to 3 months,” said Guillaume Stewat-Jones, a Moderna (ticker: MRNA) scientist who works as associate director of antigen design and selection on their infectious disease team. “And new viral variants are coming — emerging constantly in real time.” The company offered an overview of a range of its scientific programs in the presentation, including discussions on the engineering of its messenger RNA and the performance of the lipid nanoparticles that enclose the messenger RNA particles. Analyst questions at the end of the call, however, focused almost entirely on its Covid-19 vaccines. That is another sign of the importance the vaccine to the current valuation of Moderna (ticker: MRNA) shares, as SVB Leerink analyst Mani Foroohar wrote in a note out Thursday. In a separate note, Jefferies analyst Michael Yee wrote that the presentation demonstrated Moderna’s leadership in messenger RNA-based therapeutics. “[Management] is investing in engineering to ensure they have ‘ differentiated’ mRNA constructs… and this will be a key ‘moat’ to just anyone being able to ‘do mRNA,’” Yee wrote. Moderna shares climbed 2.3% on Thursday, and were down 0.4% on Friday. Barron’s argued in a feature in late April that Moderna shares had room to climb, and that Wall Street’s worries over its market value, which at that time was $67 billion and is now $70.5 billion, were overblown. Foroohar and Yee are more cautious. Foroohar has an Underperform rating on Moderna, at a target price of $83, while Yee has a Hold rating and a target price of $170. Moderna closed at $179.54 on Thursday, and is up 71.9% so far this year, and more than 220% over the past 12 months. 機翻如下: Moderna公司的科學家和高管們在週四的一次虛擬投資者活動中闡述了他們對抗導致 Covid-19的病毒新菌株的計畫,並表示新一波的疫情正在到來。 "該公司的首席科學官Melissa Moore在電話會議上說:"隨著病毒的傳播,它正在迅速變 異。"其中一些新的病毒株似乎比原來的病毒株更具傳播性......我們已經知道,這些新 的病毒株中的一些不太容易被我們目前的疫苗中和。 該公司說,它在實驗室中針對其疫苗測試新的變種,並 "不斷" 製造和測試其疫苗的新版 本。但它警告說,這個過程不是即時的,而且公司的敏捷性受到工作複雜性的限制。 Moderna(股票代碼:MRNA)的科學家Guillaume Stewat-Jones說:"從檢測到一個令人關 注的變體到針對一組假病毒的臨床前免疫原性讀出,最短的時間大約是2到3個月,"他在 傳染病團隊中擔任抗原設計和選擇副主任。"而且新的病毒變體正在出現--即時地不斷出 現。" 該公司在演講中對其一系列科學項目進行了概述,包括討論其信使RNA的工程和包裹信使 RNA顆粒的脂質納米顆粒的性能。 然而,在電話會議結束時,分析師的問題幾乎完全集中在其Covid-19疫苗上。SVB Leerink的分析師Mani Foroohar在週四發佈的一份說明中寫道,這也是疫苗對Moderna( 股票代碼:MRNA)股票當前估值的重要性的另一個跡象。 傑富瑞分析師Michael Yee在另一份報告中寫道,該報告顯示了Moderna在基於信使RNA的 治療方面的領先地位。 "Yee寫道:"[管理層]正在對工程進行投資,以確保他們擁有'差異化'的mRNA構建體 ......這將是任何人能夠'做mRNA'的關鍵'護城河'。 Moderna股價在週四攀升了2.3%,週五下跌了0.4%。 巴倫週刊》在4月底的一篇專題報導中認為,Moderna股價還有攀升的空間,華爾街對其市 場價值的擔憂被誇大了,當時的市值是670億美元,現在是705億美元。 Foroohar 和 Yee 更加謹慎。 Foroohar 對 Moderna 的評級為跑輸大盤,目標價為 83 美元,而 Yee 的評級為持有,目標價為 170 美元。 Moderna 週四收於 179.54 美元, 今年迄今上漲了 71.9%,過去 12 個月上漲了 220% 以上。 心得/評論: 說實在的MRNA已經炒很高了 不過病毒的變異性就擺在那邊 儘管還有很多疑慮 但是目前能夠最快又最有效的應對新型變種病毒的疫苗技術 還是唯一看好mRNA 沒有辦法自己做疫苗的國家 將來勢必要每年捧著幾百億去MRNA公司門口跪著求賣 長多啦長多 -- ※ 發信站: 批踢踢實業坊(ptt.cc), 來自: 180.217.37.18 (臺灣) ※ 文章網址: https://www.ptt.cc/bbs/Stock/M.1622466330.A.71A.html
slrmbenz : 新一波疫情不是早在亞洲大爆發了嗎= = 05/31 21:06
ying0502 : 跟流感一樣每年打一次… 05/31 21:06
ying0502 : 希望印度變種別進來台灣,東南亞廣州都淪陷了,怕 05/31 21:07
pippen2002 : yes~ I know! 05/31 21:07
beavertail97: 傳染無國界 05/31 21:10
jakewu1217 : 早來了不是... 05/31 21:11
SRadiant : 一開始大家都要打兩劑,之後每年補一劑,營收會成 05/31 21:13
SRadiant : 長還是衰退? 05/31 21:13
ying0502 : 本土這波不都英國變種,有印度了的嗎? 05/31 21:14
nangle : 每年兩到三組變異,政府又不可能年年補助 05/31 21:16
nangle : 其他技術的公司根本跟不上這個進度 05/31 21:17
nangle : 市場到最後一定被MRNA全吃啦 05/31 21:17
homeaki : 得過疫情痊癒 遇到變異病毒會如何 有人研究過嗎 05/31 21:19
nangle : 有沒有破防沒人知道,但是沒辦法不當一回事 05/31 21:20
nangle : 疫苗效力會衰減是確定的了 05/31 21:21
Severine : 我只後悔眼光太短 150沒買.. 05/31 21:24
Toge : 基本上BNTX和MRNA可以長期投資 05/31 21:25
linkmusic : 日本是說這病毒有登革熱的特性,二次感染重症化機率 05/31 21:25
linkmusic : 高 05/31 21:25
Francix : 明知有下波,猛打國產疫苗對台灣有何好處? 05/31 21:36
aynmeow5566 : 敢今天美股沒開 手在抖了 05/31 21:36
ck326 : MRNA 股價也是上上下下的,要買都有機會拉 05/31 21:42
huk40199 : 前幾天的新聞了 05/31 21:42
huk40199 : 但會被嗆八卦仔 05/31 21:42
fenix220 : 支那到底做出甚麼樣的怪物病毒.... 05/31 21:53
firelin : 台灣有國慘啊,怕什麼... 05/31 21:56
firelin : 國慘可以打包了,落後太多又快速變異 05/31 21:57
kamichu : 微脂體包裹? 05/31 21:58
adagiox : 爽賺 05/31 22:24
adagiox : 明年30億產能拉出來 爽賺 05/31 22:24
budda : 剛剛看醫生分析,不同疫苗對變種病毒的防禦力差別 05/31 22:48
budda : 很大,所以不要以為打了就完全沒事,更別說不打了, 05/31 22:48
budda : 因為台灣目前流行的英國變種還不是最強的,而且未 05/31 22:48
budda : 來還不知道是否面臨更強大的變種侵台,因此,要進口 05/31 22:48
budda : 更有效率的品牌疫苗也是重要的。(新聞中比較,AZ 05/31 22:48
budda : 防護力相對其他牌為低) 05/31 22:48
sdamel : 業配啦 05/31 22:49
w9103 : 組疫苗ETF拉 ~ 05/31 22:50
nakayamayyt : 變來變去還混種 真強 05/31 23:04
fuzzer : mRNA這半年波浪很大,有2次都修正30%以上沒在客氣的 05/31 23:34
gibbs1286 : 想賣第三針齁 05/31 23:43
joygo : 什麼時候有可能有類似克流感這種,還是因為它病毒在 05/31 23:51
joygo : 下呼吸道所以都來不及吃呢 05/31 23:51
dearevan : 病毒的變種是必然的 05/31 23:53
Hirano : 來了~他們來了~我們是他們的奴隸~ 06/01 00:39
zebirlin : 但高端聯亞是做蛋白質疫苗喔 06/01 00:40
kanyewest927: 疫苗能比威爾剛賺?真的變種疫苗根得上?生技夢啊 06/01 08:37